Acyl-CoA dehydrogenases are flavoproteins that catalyze the first stepof@-oxidation, converting a fatty acyl thioester substrate to the corresponding cr, B-enoyl-CoA product.'On the basis of the preferred chain length of the substrates, this class of enzymes can be further divided into three subgroups: long-chain (LCAD), medium-chain (MCAD), and short-chain (SCAD) acyl-CoA dehydrogenase.'Since these enzymes are closely related, having ...
