Tetrahedron

Building units for N-backbone cyclic peptides. 2. Synthesis of protected N-(ω-thioalkylene) amino acids and their incorporation into dipeptide units

G Bilan, C Gilon

文献索引：Bilan, Gal; Gilon, Chaim Tetrahedron, 1995 , vol. 51, # 38 p. 10513 - 10522

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被引用次数: 30

摘要

A new family of amino acids which contain an ω-thtoalkylene group on the Na-amino nitrogen was synthesized by alkylation of ω-thioalkylamines with triflates of α-hydroxy acids. The reaction proceeded with inversion of configuration yielding optically pure products. The