Novel para-substituted benzyl ethers for hydroxyl group protection

L Jobron, O Hindsgaul

文献索引：Jobron, Laurence; Hindsgaul, Ole Journal of the American Chemical Society, 1999 , vol. 121, # 24 p. 5835 - 5836

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被引用次数: 47

摘要

The observation that p-hydroxybenzyl ethers readily decompose under basic conditions to yield the free alcohol has allowed the development of novel solution-cleavable benzyl ethers as protecting groups in carbohydrate chemistry. The O-benzyl group is the most commonly used “persistent” protecting group in carbohydrate chemistry, where it is almost always removed at the last step of multistep oligosaccharide synthesis by hydrogenolysis ...