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Facile Approach to Natural or Non??Natural Amino Acid Derivatives: Me3SiCl??Promoted Coupling Reaction of Organozinc Compounds with N, O??Acetals

…, J Asano, Y Kawada, T Konakahara

文献索引:Sakai, Norio; Asano, Junichi; Kawada, Yuki; Konakahara, Takeo European Journal of Organic Chemistry, 2009 , # 6 p. 917 - 922

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被引用次数: 2

摘要

Abstract We have developed a Me 3 SiCl-promoted coupling reaction of aryl-and alkylzinc compounds, in-situ generated either by transmetalation of the corresponding organometallic reagents or by insertion of zinc metal into organic halides, with several N, O-acetals, which leads to the preparation of a variety of natural and non-natural amino acid derivatives.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)