An improved method for the palladium cross-coupling reaction of oxazol-2-ylzinc derivatives with aryl bromides

…, SA Hoover, RJ Imbordino, JJ Pangborn

文献索引：Reeder, Michael R.; Gleaves, Harold E.; Hoover, Sheree A.; Imbordino, Rick J.; Pangborn, Jeffrey J. Organic Process Research and Development, 2003 , vol. 7, # 5 p. 696 - 699

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被引用次数: 38

摘要

An improved and scalable procedure to couple ozaxole and thiazole to aryl halides has been demonstrated. The required organozinc reagents were prepared from the aryllithium and solid ZnCl2. These reagents have been successfully coupled to a variety of aryl bromides and aryl iodides in good to excellent yields.