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Synthetic communications

Efficient synthesis of 4-ethoxycarbonyl pyrazolin-5-one derivatives

JC Jung, EB Watkins, MA Avery

文献索引:Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A. Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777

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被引用次数: 13

摘要

ABSTRACT Concise and efficient methods for the preparation of 3-substituted 4- ethoxycarbonylpyrazolin-5-ones are described. The synthetic strategies involve carbon- acylation in the presence of base, followed by ring cyclization with hydrazine or hydrazine monohydrochloride.