Diastereoselective Spirocyclization of Imines of 2??Substituted 1H??Indole??3??ethylamines (= Trypatamines): Variation of the electrophile and the substituent at C (2) and …
Abstract Tryptimines of type 7 form with various acyl halogenides EX preferentially tricycles of type 8 (cf: Scheme 2). The homochiral imines 9 and 17 are transformed into (2′ R, 3S)- configurated products. The synthetic and mechanistic importance of these results is