Synthesis and antiviral activities of carbocyclic oxetanocin analogues.

…, Y Sato, T Horii, H Shiota, K Nitta, T Shirasaka…

文献索引：Maruyama; Sato; Horii; Shiota; Nitta; Shirasaka; Misuya; Honjo Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 10 p. 2719 - 2725

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被引用次数: 38

摘要

9-Cyclobutyladenine (4a), cis-and trans-9-[3-(hydr0xymethyl) cyclohutyl] adenine (4b) and 9- [3, 3-bis (hydroxymethyl) cyclobutyl] adenine (4d) were prepared from the corresponding cyclobutylamine derivatives (1a, 1b and 1d). Guanine congeners (9a, cis-and trans-9b and 9d) and carbocyclic oxetanocin G (1', 2'-trans-9f) were also prepared. Carbocyclic oxetanocin A (1', 2'-trans-4f), the preparation of which we have already published, and G ...