The Journal of Organic Chemistry

Microwave-promoted palladium-catalyzed coupling reactions

M Larhed, A Hallberg

文献索引：Larhed, Mats; Hallberg, Anders Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9582 - 9584

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被引用次数: 351

摘要

The intermolecular Heck reaction of aryl halides or aryl triflates with olefins is of the utmost importance in organic synthesis. 1 With a few exceptions, 2-4 most substrates for coupling require reaction temperatures of 70-100 C1e and reaction times ranging from hours to days for full conversion. Attempts to reduce the reaction time by enhancing the temperature are seldom effective due to collapse of the catalytic system. 1d, 5, 6 Therefore, access to ...