Facile one step synthesis of acyl azides and Nα-Fmoc/Boc/Z protected amino acid azides employing benzotriazole-1-yl-oxy-tris-(dimethyl-amino)-phosphonium …

B Vasantha, VV Sureshbabu

文献索引：Vasantha; Sureshbabu, Vommina V. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010 , vol. 49, # 6 p. 812 - 817

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被引用次数: 6

摘要

Abstract: A simple route for the preparation of acyl azides from the corresponding carboxylic acids employing the peptide-coupling agent BOP is described. The procedure is simple, clean and high yielding. The chemistry is also extended to the preparation of several urethane protected amino acid azides (eight examples) as well.