Tetrahedron letters

A copper-and amine-free Sonogashira coupling reaction promoted by a ferrocene-based phosphinimine-phosphine ligand at low catalyst loading

A Arques, D Aunon, P Molina

文献索引：Arques, Antonio; Aunon, David; Molina, Pedro Tetrahedron Letters, 2004 , vol. 45, # 22 p. 4337 - 4340

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被引用次数: 84

摘要

A palladium (II) complex containing a ferrocene-based phosphinimine-phosphine ligand was applied to the amine-and copper-free Sonogashira coupling of aryl iodides and aryl bromides with terminal alkynes using 1equiv of tetrabutylammonium acetate as an activator. The corresponding disubstituted alkynes were obtained in high yields and TONs using 0.1 mol% Pd-catalyst.