General catalysts for the Suzuki–Miyaura and Sonogashira coupling reactions of aryl chlorides and for the coupling of challenging substrate combinations in water

KW Anderson, SL Buchwald

文献索引：Anderson, Kevin W.; Buchwald, Stephen L. Angewandte Chemie - International Edition, 2005 , vol. 44, # 38 p. 6173 - 6177

全文：HTML全文

被引用次数: 357

摘要

Metal-catalyzed cross-coupling methodology to form carbon–carbon bonds has inarguably advanced organic synthesis.[1] The Suzuki–Miyaura coupling is one of the preeminent methods for formation of carbon–carbon bonds and has been used in numerous synthetic ventures.[2] We recently reported a new catalyst system that manifested high activity paired with extremely broad scope.[3] There remained, however, a need to develop reaction ...