Synthesis of dibenzo [g, p] chrysenes from bis (biaryl) acetylenes via sequential ICl-Induced cyclization and Mizoroki-Heck coupling

CW Li, CI Wang, HY Liao, R Chaudhuri…

文献索引：Li, Chia-Wen; Wang, Cheng-I.; Liao, Hsin-Yi; Chaudhuri, Rupsha; Liu, Rai-Shung Journal of Organic Chemistry, 2007 , vol. 72, # 24 p. 9203 - 9207

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被引用次数: 67

摘要

We report a facile synthesis of functionalized dibenzo [g, p] chrysenes via initial ICl- promoted cyclization of bis (biaryl) acetylenes, followed by the Mizoroki-Heck coupling reaction. This new approach works well for various bis (biaryl) acetylenes to afford dibenzo [g, p] chrysenes bearing various functionalities. With substrates of one special type including 4'-methoxy-2-ethynylbiphenyls, we found that the ICl treatment led to ipso cyclization to ...