Synthesis and evaluation of ω-borono-α-amino acids as active-site probes of arginase and nitric oxide synthases

…, M Lepoivre, R Danion-Bougot, D Danion

文献索引：Collet, Sylvain; Carreaux, Francois; Boucher, Jean-Luc; Pethe, Stephanie; Lepoivre, Michel; Danion-Bougot, Renee; Danion, Daniel Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 2 p. 177 - 182

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被引用次数: 39

摘要

Enantiomerically pure ω-borono-α-amino acids of various chain lengths have been synthesized according to a general methodology involving condensation of alkenyl and alkynyl bromides with Ni II complex of the Schiff base derived from glycine and (S [hair space])-2-[N [hair space]′-(N-benzylprolyl) amino] benzophenone, hydroboration of the intermediate ω-unsaturated α-amino acids with diisopinocampheylborane, and oxidation ...