Enantiomerically pure ω-borono-α-amino acids of various chain lengths have been synthesized according to a general methodology involving condensation of alkenyl and alkynyl bromides with Ni II complex of the Schiff base derived from glycine and (S [hair space])-2-[N [hair space]′-(N-benzylprolyl) amino] benzophenone, hydroboration of the intermediate ω-unsaturated α-amino acids with diisopinocampheylborane, and oxidation ...
