Tetrahedron Letters

Generation and reactions of 2, 3-dilithio-N-methylindole. Synthesis of 2, 3-disubstituted indoles

Y Liu, GW Gribble

文献索引：Liu, Yanbing; Gribble, Gordon W. Tetrahedron Letters, 2001 , vol. 42, # 16 p. 2949 - 2951

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被引用次数: 31

摘要

Generation of 2, 3-dilithio-N-methylindole (7) from 2, 3-diiodo-N-methylindole (6) and subsequent reaction with various electrophiles (NH4Cl, DMF, ClCO2Me, CO2, phthalic anhydride) affords the corresponding 2, 3-disubstituted indoles in good to excellent yields