Tetrahedron

Palladium-catalyzed arylation of polar organometallics mediated by 9-methoxy-9-borabicyclo [3.3. 1] nonane: Suzuki reactions of extended scope

A Fürstner, G Seidel

文献索引：Fuerstner, Alois; Seidel, Guenter Tetrahedron, 1995 , vol. 51, # 41 p. 11165 - 11176

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被引用次数: 118

摘要

An alternative way for performing Suzuki reactions is presented. The necessary borate which is the actual nucleophile in these palladium catalyzed CC-bond formations is prepared from 9-methoxy-9-bora-bicyclo [3.3. 1] nonane (9-OMe-9-BBN) and a polar organometallic reagent RM, and not as usually from a borane and a base. This approach allows cross couplings of aryl halides with eg alkynyl-, methyl-, or TMSCH2-groups, which ...