Total synthesis of (-)-balanol

…, PF Hughes, CK Biggers, SH Smith, H Hu

文献索引：Lampe, John W.; Hughes, Philip F.; Biggers, Christopher K.; Smith, Shelley H.; Hu, Hong Journal of Organic Chemistry, 1994 , vol. 59, # 18 p. 5147 - 5148

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被引用次数: 85

摘要

Summary:(-)-Balanol, a fungal metabolite with potent protein kinase C inhibitory properties, has been prepared in a total synthesis which makes use of an anionic homo-Fries rearrangement approach to the benzophenone subunit and in which the azepane subunit is obtained from (2S, 3R)-3-hydroxylysine.