e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Total synthesis of (-)-balanol
…, PF Hughes, CK Biggers, SH Smith, H Hu
Index: Lampe, John W.; Hughes, Philip F.; Biggers, Christopher K.; Smith, Shelley H.; Hu, Hong Journal of Organic Chemistry, 1994 , vol. 59, # 18 p. 5147 - 5148
Summary:(-)-Balanol, a fungal metabolite with potent protein kinase C inhibitory properties, has been prepared in a total synthesis which makes use of an anionic homo-Fries rearrangement approach to the benzophenone subunit and in which the azepane subunit is obtained from (2S, 3R)-3-hydroxylysine.
