前往化源商城

Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors of Heat Shock Protein 90. Identification of Development …

L Zehnder, M Bennett, J Meng, B Huang…

文献索引:Journal of Medicinal Chemistry, , vol. 54, # 9 p. 3368 - 3385

全文:HTML全文

被引用次数: 23

摘要

... Journal of Medicinal Chemistry. ... In this report, we describe our medicinal chemistry efforts that afforded a novel class of Hsp90 inhibitors that exhibit potent efficacy in animal tumor models along with other desirable pharmaceutical properties. figure ...