e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors of Heat Shock Protein 90. Identification of Development …
L Zehnder, M Bennett, J Meng, B Huang…
Index: Journal of Medicinal Chemistry, , vol. 54, # 9 p. 3368 - 3385
... Journal of Medicinal Chemistry. ... In this report, we describe our medicinal chemistry efforts that afforded a novel class of Hsp90 inhibitors that exhibit potent efficacy in animal tumor models along with other desirable pharmaceutical properties. figure ...