Synlett

Poly (ethylene glycol) Supported Liquid Phase Synthesis of Biaryls

CG Blettner, WA König, W Stenzel, T Schotten

文献索引：Blettner, Carsten G.; Koenig, Wilfried A.; Stenzel, Wolfgang; Schotten, Theo Synlett, 1998 , # 3 p. 295 - 297

全文：HTML全文

被引用次数: 29

摘要

Abstract: The liquid phase synthesis of biaryls via Suzuki crosscoupling reaction on poly (ethylene glycol) supports (PEGs) is described. The reaction is exemplified by parallel coupling of polymer bound aryl halides with boronic acids. Four different PEGs were employed as soluble polymer supports for parallel synthesis. The generated libraries include both sterically hindered aryl halides (2b, 2d) and boronic acids. The reactions ...