Chemistry Letters

Synthetic utility of propylphosphonic anhydride–DMSO media: an efficient one-pot three-component synthesis of 2-arylquinolines

KH Narasimhamurthy, S Chandrappa, KSS Kumar…

文献索引：Narasimhamurthy, Kereyagalahally H.; Chandrappa, Siddappa; Kumar, Kothanahally S. Sharath; Swaroop, Toreshettahally R.; Rangappa, Kanchugarakoppal S. Chemistry Letters, 2013 , vol. 42, # 9 p. 1073 - 1075

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被引用次数: 4

摘要

Propylphosphonic anhydride (T3P®)–DMSO-mediated one-pot three-component synthesis which provides 2-arylquinolines in a single step from benzyl alcohols, anilines, and ethyl vinyl ether by the modified Povarov reaction has been demonstrated. T3P®–DMSO is a mild and low-toxic peptide coupling agent and an easy to handle reagent for bulk reactions at room temperature.