Synthesis of analogs of 1, 3-dihydroxyacetone phosphate and glyceraldehyde 3-phosphate for use in studies of fructose-1, 6-diphosphate aldolase

N Bischofberger, H Waldmann, T Saito…

文献索引：Bischofberger, Norbert; Waldmann, Herbert; Saito, Tohru; Simon, Ethan S.; Lees, Watson; et al. Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3457 - 3465

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被引用次数: 97

摘要

This paper describes the syntheses of five analogues of dihydroxyacetone phosphate (3- azidohydroxyacetone 1-phosphate (5), 3-(acetylamino) hydroxyacetone 1-phosphate (12),(R)-1, 3-dihydroxy-2-butanone 1-phosphate (18),(*)-1, 3-dihydroxy-2-butanone 3- phosphate (26), and phosphonomethyl glycolate (31)). The syntheses of 18 and 26 are based on a new reaction: that is, the introduction of the phosphate group by reaction of a ...