5′-O-Alkylpyridoxamines: Lipophilic Analogues of Pyridoxamine Are Potent Scavengers of 1, 2-Dicarbonyls

V Amarnath, K Amarnath, J Avance…

文献索引：Zagol-Ikapitte, Irene; Amarnath, Venkataraman; Bala, Manju; Roberts II, L. Jackson; Oates, John A.; Boutaud, Olivier Chemical Research in Toxicology, 2010 , vol. 23, # 1 p. 240 - 250

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被引用次数: 3

摘要

Pyridoxamine (PM) is a prospective drug for the treatment of diabetic complications. In order to make zwitterionic PM more lipophilic and improve its tissue distribution, PM derivatives containing medium length alkyl groups on the hydroxymethyl side chain were prepared. The