Tetrahedron Letters

Synthesis of quinolines by a solid acid-catalyzed microwave-assisted domino cyclization–aromatization approach

O De Paolis, L Teixeira, B Toeroek

文献索引：De Paolis, Omar; Teixeira, Liliana; Toeroek, Bela Tetrahedron Letters, 2009 , vol. 50, # 24 p. 2939 - 2942

全文：HTML全文

被引用次数: 39

摘要

A microwave-assisted solid acid-catalyzed synthesis of quinolines from anilines and cinnamaldehydes is described. Use of montmorillonite K-10 results in a one-pot process; the cyclization and oxidation steps readily take place in a domino approach. Reactions were completed in a matter of minutes and provided excellent yields. The efficient and ecofriendly catalyst and the convenience of the product isolation make this process an attractive ...