An efficient catalytic asymmetric epoxidation method

ZX Wang, Y Tu, M Frohn, JR Zhang…

文献索引：Wang, Zhi-Xian; Tu, Yong; Frohn, Michael; Zhang, Jian-Rong; Shi, Yian Journal of the American Chemical Society, 1997 , vol. 119, # 46 p. 11224 - 11235

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被引用次数: 597

摘要

This article describes a highly effective catalytic asymmetric epoxidation method for olefins using potassium peroxomonosulfate (Oxone, Dupont) as oxidant and a fructose-derived ketone (1) as catalyst. High enantioselectivies have been obtained for trans-disubstituted and trisubstituted olefins which can bear functional groups such as tributylsilyl ether, acetal, chloride, and ester. The enantiomeric excesses for cis-olefins and terminal olefins are not ...