Aminoalkylphenothiazines

RB Moffett, BD Aspergren

文献索引：Moffett,R.B.; Aspergren,B.D. Journal of the American Chemical Society, 1960 , vol. 82, p. 1600 - 1607

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被引用次数: 26

摘要

The preparation of a number of new 10-arninoalkyl-(I) and 10-aminoalkanol-(11) phenothiazincs is reported. Tllc:~ compounds have been screened for their ability to increase the sleeping time of mlce given hexobarbital, a test which has been used to select compounds for trial in mental disease. The sulfoxides (VI11 and S, N-dioxides (VIII) of several of these compounds were prepared and found to be very active diuretics. Several ...