Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition

HS Parekh, RJ Marano, EP Rakoczy…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 14, # 14 p. 4775 - 4780

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被引用次数: 26

摘要

... Bioorganic & Medicinal Chemistry. ... Dendrimers were synthesized using stepwise solid-phase Boc-chemistry (see Table 1 and Table 2). Glycodendrimers 40–45 incorporated building block 6b coupled via the acid to the ε-NH 2 termini of l-lysine (Fig. ...