Comparative potencies of 3, 4??methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H] noradrenaline and [3H] 5??HT transport in …

T Montgomery, C Buon, S Eibauer…

文献索引：Montgomery; Buon; Eibauer; Guiry; Keenan; McBean British Journal of Pharmacology, 2007 , vol. 152, # 7 p. 1121 - 1130

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被引用次数: 21

摘要

Background and purpose: Illegal 'ecstasy'tablets frequently contain 3, 4- methylenedioxymethamphetamine (MDMA)-like compounds of unknown pharmacological activity. Since monoamine transporters are one of the primary targets of MDMA action in the brain, a number of MDMA analogues have been tested for their ability to inhibit [3 H] noradrenaline uptake into rat PC12 cells expressing the noradrenaline transporter (NET) ...