Background and purpose: Illegal 'ecstasy'tablets frequently contain 3, 4- methylenedioxymethamphetamine (MDMA)-like compounds of unknown pharmacological activity. Since monoamine transporters are one of the primary targets of MDMA action in the brain, a number of MDMA analogues have been tested for their ability to inhibit [3 H] noradrenaline uptake into rat PC12 cells expressing the noradrenaline transporter (NET) ...
