The Strecker reaction has been one of the most important and useful C–C bond forming processes in organic synthesis, 1 since the α-amino nitrile products serve not only as the synthetic intermediates for α-amino acids, but also as versatile synthons in organic chemistry. 1a,2 Numerous modifications have been made to the original conditions, using aqueous media to improve the efficiency of this process. However, due to the reversible nature of the reaction, most modified ...
