Decomposition of formamide assisted by microwaves, a tool for synthesis of nitrogen-containing heterocycles

I Nouira, IK Kostakis, C Dubouilh, E Chosson…

文献索引：Nouira, Ines; Kostakis, Ioannis K.; Dubouilh, Carole; Chosson, Elizabeth; Iannelli, Mauro; Besson, Thierry Tetrahedron Letters, 2008 , vol. 49, # 49 p. 7033 - 7036

全文：HTML全文

被引用次数: 44

摘要

Generation of ammonia via thermal decomposition of formamide was studied under microwave conditions to provide an efficient tool for the synthesis of nitrogen-containing heterocycles. Quinazolin-4-ones, which are known as building blocks for molecules with pharmaceutical interest, were chosen as examples. Our work confirms that reactants may have different behaviours under microwaves, depending on power input, reached ...