Bulletin of the chemical society of japan

Benign and efficient synthesis of 2-substituted 4 (3H)-quinazolinones mediated by iron (III) chloride hexahydrate in refluxing water

GW Wang, CB Miao, H Kang

文献索引：Wang, Guan-Wu; Miao, Chun-Bao; Kang, Hui Bulletin of the Chemical Society of Japan, 2006 , vol. 79, # 9 p. 1426 - 1430

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被引用次数: 45

摘要

Condensation of aldehydes with anthranilamide in refluxing water using iron (III) chloride hexahydrate as an oxidiant afforded 2-substituted 4 (3H)-quinazolinones in good yields (77– 93%). This method provides several advantages such as being environmentally friendly, having a simple work-up procedure, and affording high yields.