2-Amino-5-substituted oxazolines and intermediates as potential anorectants

ER Freiter, AH Abdallah, SJ Strycker

文献索引：Freiter,E.R. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, # 5 p. 510 - 512

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被引用次数: 4

摘要

The synthesis of some 2-amino-5-arylthiomethyloxazolines and intermediates is reported. These compounds and some of their intermediates although less active than d- amphetamine were found to have significant anorectant activity. The most active in this series was found to be 2-amino-5-(phenylthiomethy1) oxazoline (7a) and caused a significant decrease in the food intake of male albino rats when compared to controls.