Dirhodium (II) tetrakis [N-tetrafluorophthaloyl-(S)-tert-leucinate]: an exceptionally effective Rh (II) catalyst for enantiotopically selective aromatic C–H insertions of diazo …

H Tsutsui, Y Yamaguchi, S Kitagaki, S Nakamura…

文献索引：Tsutsui, Hideyuki; Yamaguchi, Yukiko; Kitagaki, Shinji; Nakamura, Seiichi; Anada, Masahiro; Hashimoto, Shunichi Tetrahedron Asymmetry, 2003 , vol. 14, # 7 p. 817 - 821

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被引用次数: 67

摘要

Dirhodium (II) tetrakis [N-tetrafluorophthaloyl-(S)-tert-leucinate], Rh2 [(S)-TFPTTL] 4, in which the phthalimido hydrogen atoms of the parent dirhodium (II) complex are substituted by fluorine atoms, dramatically enhances the reactivity and enantioselectivity (up to 97% ee) in intramolecular aromatic C–H insertion reactions of methyl 4-alkyl-2-diazo-4, 4-diphenyl-3- oxopropionates. Catalysis with the use of 0.001 mol% of Rh2 [(S)-TFPTTL] 4 has achieved ...