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Tetrahedron

Expeditious preparation of triazole-linked glycolipids via microwave accelerated click chemistry and their electrochemical and biological assessments

…, HL Zhang, CG Kim, L Sheng, XP He, YT Long, J Li…

文献索引:Song, Shao-Xing; Zhang, Hai-Lin; Kim, Chol-Guk; Sheng, Li; He, Xiao-Peng; Long, Yi-Tao; Li, Jia; Chen, Guo-Rong Tetrahedron, 2010 , vol. 66, # 52 p. 9974 - 9980

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被引用次数: 39

摘要

A series of triazole-linked ester-type glycolipids were efficiently prepared via a two-step sequence involving microwave accelerated 'click'chemistry and debenzylation. All carbon chain length varied O-alkynyl fatty esters used to couple with 1-azido-tetra-O-benzyl-β-d- glucoside showed excellent tolerance to the microwave-assisted 1, 3-dipolar cycloaddition (click reaction), forming the unique cycloadducts in almost quantitative yields of 92.9–99.0 ...