Journal of pharmaceutical sciences

Thiophosphoric acid derivatives of ethylamine, DL??methionine, and L??proline ethyl esters I. Synthesis

FC Klee, ER Kirch

文献索引：Klee,F.C.; Kirch,E.R. Journal of Pharmaceutical Sciences, 1962 , vol. 51, p. 423 - 427

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被引用次数: 5

摘要

Abstract Thiophosphoric acid derivatives having structures similar to known anticholinesterases, were synthesized for the investigation of their possible enzyme inhibition in vivo. Based on theoretical considerations concerning structures of known chemotherapeutic agents, these compounds may possess antitumor activity. The phenyl ester was found to be white needle-like crystals rather than the liquid reported by ...