Metal alkoxide modified organometallic reagents. Preparation and stability of organolithium reagents in tetrahydrofuran in the presence of magnesium 2- …
CG Screttas, BR Steele
文献索引：Screttas, Constantinos G.; Steele, Barry R. Journal of Organic Chemistry, 1989 , vol. 54, # 5 p. 1013 - 1017
The metalating ability of alkyllithium reagents and their tendency to cleave THF are greatly diminished in the presence of magnesium 2-ethoxyethoxide, 1. Advantage may be taken of this to generate organolithium reagents in THF in the presence of 1 under conditions not normally favorable to their stability. Thus, by reaction with metallic lithium in the presence of 1 in THF, the compounds RX (R= n-Bu, s-Bu, t-Bu, cyclohexyl, menthyl, p-methoxyphenyl, ...
