Ionic liquid mediated Cu-catalyzed cascade oxa-Michael-oxidation: efficient synthesis of flavones under mild reaction conditions

Z Du, H Ng, K Zhang, H Zeng, J Wang

文献索引：Du, Zhiyun; Ng, Huifen; Zhang, Kun; Zeng, Huaqiang; Wang, Jian Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 6930 - 6933

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被引用次数: 29

摘要

Flavonoids are a class of natural products, found in a wide range of vascular plants and dietary components. Their low toxicity and extensive biological activities, including anti- cancer and anti-bacterial, have made them attractive candidates to serve as therapeutic agents for many diseases. Herein, we disclose a highly efficient synthetic method of CuI- catalyzed cascade oxa-Michael-oxidation, using chalcones as substrates, mediated by the ...