20-(Tert-Butoxy)-20-Oxoicosanoic Acid
Modify Date: 2024-01-03 12:46:22
20-(Tert-Butoxy)-20-Oxoicosanoic Acid structure
|
Common Name | 20-(Tert-Butoxy)-20-Oxoicosanoic Acid | ||
|---|---|---|---|---|
| CAS Number | 683239-16-9 | Molecular Weight | 398.620 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 496.0±18.0 °C at 760 mmHg | |
| Molecular Formula | C24H46O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 152.4±14.7 °C | |
Use of 20-(Tert-Butoxy)-20-Oxoicosanoic Acid20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 20-(tert-Butoxy)-20-oxoicosanoic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs |
| Name | 20-(Tert-Butoxy)-20-Oxoicosanoic Acid |
|---|---|
| Synonym | More Synonyms |
| Description | 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 20-(tert-Butoxy)-20-oxoicosanoic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 496.0±18.0 °C at 760 mmHg |
| Molecular Formula | C24H46O4 |
| Molecular Weight | 398.620 |
| Flash Point | 152.4±14.7 °C |
| Exact Mass | 398.339600 |
| PSA | 63.60000 |
| LogP | 8.87 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.463 |
| Water Solubility | Insuluble (2.0E-4 g/L) (25 ºC) |
| Eicosanedioic acid, mono(1,1-dimethylethyl) ester |
| 20-[(2-Methyl-2-propanyl)oxy]-20-oxoicosanoic acid |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: 20-(tert-Butoxy)-20-oxoicosanoic acid
- Price: ￥Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: 20-(Tert-Butoxy)-20-Oxoicosanoic Acid
- Price: ￥Inquiry/10g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: 20-(tert-Butoxy)-20-oxoicosanoic acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Nanjing Peptide Biotech Ltd
- China
- Product Name: 20-(tert-Butoxy)-20-oxoicosanoic acid
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 20-(tert-Butoxy)-20-oxoicosanoic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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