CP-20961

Modify Date: 2024-01-09 11:44:29

CP-20961 structure	Common Name	CP-20961
	CAS Number	35607-20-6	Molecular Weight	667.18700
	Density	0.892g/cm3	Boiling Point	717.6ºC at 760mmHg
	Molecular Formula	C₄₃H₉₀N₂O₂	Melting Point	N/A
	MSDS	USA	Flash Point	294.3ºC

Use of CP-20961

CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[1][2].

Name	2-[3-(dioctadecylamino)propyl-(2-hydroxyethyl)amino]ethanol
Synonym	More Synonyms

Description	CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Avridine-induced arthritis is severe and long lasting in LEW and DA rats[2]. CP-20961 (10 mg/kg, i.v., once either 24, 48, or 72 hours post-burn) had no effect on survival after challenge with P. aeruginosa 96 hours post-burn[3]. Animal Model: Female, Hartley-derived guinea pigs, weighing 350 to 400 g[3]. Dosage: 10 mg/kg. Administration: IV once either 24, 48, or 72 hours post-burn. Result: Had no effect on survival after challenge with P. aeruginosa 96 hours post-burn.
References	[1]. Brun JG, et al. Effects of calprotectin in avridine-induced arthritis. APMIS. 1995 Mar;103(3):233-40. [2]. Vingsbo C, et al. Avridine-induced arthritis in rats; a T cell-dependent chronic disease influenced both by MHC genes and by non-MHC genes. Clin Exp Immunol. 1995 Mar;99(3):359-63. [3]. Stinnett JD, et al. Synthetic immunomodulators for prevention of fatal infections in a burned guinea pig model. Ann Surg. 1983 Jul;198(1):53-7.

Density	0.892g/cm3
Boiling Point	717.6ºC at 760mmHg
Molecular Formula	C₄₃H₉₀N₂O₂
Molecular Weight	667.18700
Flash Point	294.3ºC
Exact Mass	666.70000
PSA	46.94000
LogP	12.48810
Index of Refraction	1.478

CP-20961 MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KK7243000

CHEMICAL NAME :: Ethanol, 2,2'-((3-(dioctadecylamino)propyl)imino)bis-

CAS REGISTRY NUMBER :: 35607-20-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C43-H90-N2-O2

MOLECULAR WEIGHT :: 667.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 3,498,1973

RIDADR	NONH for all modes of transport
RTECS	KK7243000
HS Code	2922199090

HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Identification of arthritogenic adjuvants of self and foreign origin.

Scand. J. Immunol. 49(1) , 45-50, (1999)

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A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis.

Clin. Exp. Immunol. 103(1) , 77-82, (1996)

The effects of a mycobacterial 71-kD hsp antigen have been investigated for its ability to modulate arthritis in rats. Subcutaneous injection (base of tail) of increasing amounts of hsp71 from Mycobac...

Effect of the bacillus of Calmette-Guérin, Propionibacter acnes and avridine as immunomodulators in antirabies vaccination of mice using the Fuenzalida-Palacios mouse brain vaccine.

Vaccine 17(19) , 2446-52, (1999)

Using the laboratory mice, Fuenzalida-Palacios mouse brain human rabies vaccine was administered in groups of animals previously inoculated with rabies virus and then submitted to treatments with the ...

cp-20,961

avridine

DC Chemicals Limited
China
Product Name: Avridine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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