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35607-20-6

35607-20-6 structure

35607-20-6 structure

Name: CP-20961
Chemical Name: 2-[3-(dioctadecylamino)propyl-(2-hydroxyethyl)amino]ethanol
CAS Number: 35607-20-6
Molecular Formula: C₄₃H₉₀N₂O₂
Molecular Weight: 667.18700
Catalog: Research Areas Infection
Create Date: 2018-04-11 08:00:00
Modify Date: 2024-01-09 11:44:29
CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[1][2].

Name	2-[3-(dioctadecylamino)propyl-(2-hydroxyethyl)amino]ethanol
Synonyms	cp-20,961 avridine

Description	CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Avridine-induced arthritis is severe and long lasting in LEW and DA rats[2]. CP-20961 (10 mg/kg, i.v., once either 24, 48, or 72 hours post-burn) had no effect on survival after challenge with P. aeruginosa 96 hours post-burn[3]. Animal Model: Female, Hartley-derived guinea pigs, weighing 350 to 400 g[3]. Dosage: 10 mg/kg. Administration: IV once either 24, 48, or 72 hours post-burn. Result: Had no effect on survival after challenge with P. aeruginosa 96 hours post-burn.
References	[1]. Brun JG, et al. Effects of calprotectin in avridine-induced arthritis. APMIS. 1995 Mar;103(3):233-40. [2]. Vingsbo C, et al. Avridine-induced arthritis in rats; a T cell-dependent chronic disease influenced both by MHC genes and by non-MHC genes. Clin Exp Immunol. 1995 Mar;99(3):359-63. [3]. Stinnett JD, et al. Synthetic immunomodulators for prevention of fatal infections in a burned guinea pig model. Ann Surg. 1983 Jul;198(1):53-7.

Density	0.892g/cm3
Boiling Point	717.6ºC at 760mmHg
Molecular Formula	C₄₃H₉₀N₂O₂
Molecular Weight	667.18700
Flash Point	294.3ºC
Exact Mass	666.70000
PSA	46.94000
LogP	12.48810
Index of Refraction	1.478

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KK7243000

CHEMICAL NAME :: Ethanol, 2,2'-((3-(dioctadecylamino)propyl)imino)bis-

CAS REGISTRY NUMBER :: 35607-20-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C43-H90-N2-O2

MOLECULAR WEIGHT :: 667.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 3,498,1973

RIDADR	NONH for all modes of transport
RTECS	KK7243000
HS Code	2922199090

HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%