PAR-3 (1-6) amide (mouse) trifluoroacetate salt

Modify Date: 2024-01-02 09:26:16

PAR-3 (1-6) amide (mouse) trifluoroacetate salt Structure
PAR-3 (1-6) amide (mouse) trifluoroacetate salt structure
Common Name PAR-3 (1-6) amide (mouse) trifluoroacetate salt
CAS Number 261521-21-5 Molecular Weight 576.60
Density 1.4±0.1 g/cm3 Boiling Point 1229.5±65.0 °C at 760 mmHg
Molecular Formula C25H36N8O8 Melting Point N/A
MSDS N/A Flash Point 697.4±34.3 °C

 Use of PAR-3 (1-6) amide (mouse) trifluoroacetate salt


SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)

 Names

Name L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide
Synonym More Synonyms

  Biological Activity

Description SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)
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 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1229.5±65.0 °C at 760 mmHg
Molecular Formula C25H36N8O8
Molecular Weight 576.60
Flash Point 697.4±34.3 °C
Exact Mass 576.265625
LogP -2.38
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.602

 Synonyms

L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide
L-Prolinamide, L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl-
SFNGGP-NH2 PAR3 Tethered Ligand (Murine) / Activates PAR1 and PAR2
PAR-3 (1-6) amide (mouse)