PAR-3 (1-6) amide (mouse) trifluoroacetate salt

Names

[ Name ]:
PAR-3 (1-6) amide (mouse) trifluoroacetate salt

[Synonym ]:
L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide
L-Prolinamide, L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl-
SFNGGP-NH2 PAR3 Tethered Ligand (Murine) / Activates PAR1 and PAR2
PAR-3 (1-6) amide (mouse)

Biological Activity

[Description]:

SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1229.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₆N₈O₈

[ Molecular Weight ]:
576.60

[ Flash Point ]:
697.4±34.3 °C

[ Exact Mass ]:
576.265625

[ LogP ]:
-2.38

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.602

Related Compounds

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