Raloxifene 6-Monomethyl Ether

Modify Date: 2024-01-18 16:42:35

Raloxifene 6-Monomethyl Ether structure	Common Name	Raloxifene 6-Monomethyl Ether
	CAS Number	178451-13-3	Molecular Weight	487.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₉NO₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Raloxifene 6-Monomethyl Ether

Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1].

Name	Raloxifene 6-Monomethyl Ether

Description	Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR
In Vitro	Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative with a methoxy group on C6. Raloxifene 6-Monomethyl Ether holds poor ICsub>50 value because of disruption to the hydrogen bond network and steric disfavor[1].
References	[1]. Chang YH, et al. Computational study of estrogen receptor-alpha antagonist with three-dimensional quantitative structure-activity relationship, support vector regression, and linear regression methods. Int J Med Chem. 2013;2013:743139.

Molecular Formula	C₂₉H₂₉NO₄S
Molecular Weight	487.61

DC Chemicals Limited
China
Product Name: Raloxifene 6-Monomethyl Ether
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Raloxifene 6-Monomethyl Ether

Use of Raloxifene 6-Monomethyl Ether

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Raloxifene 6-Monomethyl Ether Biological Activity

Chemical & Physical Properties