Lipoamido-PEG2-OH

Modify Date: 2024-01-11 17:40:03

Lipoamido-PEG2-OH Structure
Lipoamido-PEG2-OH structure
Common Name Lipoamido-PEG2-OH
CAS Number 1674386-82-3 Molecular Weight 337.499
Density 1.2±0.1 g/cm3 Boiling Point 546.5±35.0 °C at 760 mmHg
Molecular Formula C14H27NO4S2 Melting Point N/A
MSDS N/A Flash Point 284.3±25.9 °C

 Use of Lipoamido-PEG2-OH


Lipoamido-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Lipoamido-PEG2-alcohol
Synonym More Synonyms

 Lipoamido-PEG2-OH Biological Activity

Description Lipoamido-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 546.5±35.0 °C at 760 mmHg
Molecular Formula C14H27NO4S2
Molecular Weight 337.499
Flash Point 284.3±25.9 °C
Exact Mass 337.138153
LogP 0.47
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.532

 Synonyms

LIPOAMIDO-PEG2-OH
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