2173095-09-3

2173095-09-3 structure

2173095-09-3 structure

Name: m-PEG3-S-PEG2-OH
Chemical Name: m-PEG3-S-PEG2-OH
CAS Number: 2173095-09-3
Molecular Formula: C₁₃H₂₈O₆S
Molecular Weight: 312.42
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:11:14
Modify Date: 2024-01-29 12:42:29
m-PEG3-S-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG3-S-PEG2-OH
Synonyms	MFCD29918260

Description	m-PEG3-S-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₃H₂₈O₆S
Molecular Weight	312.42