22-(tert-Butoxy)-22-oxodocosanoic acid
Modify Date: 2024-01-01 20:52:59
22-(tert-Butoxy)-22-oxodocosanoic acid structure
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Common Name | 22-(tert-Butoxy)-22-oxodocosanoic acid | ||
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| CAS Number | 1642333-05-8 | Molecular Weight | 426.673 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H50O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 22-(tert-Butoxy)-22-oxodocosanoic acid22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t |
| Name | 22-(tert-Butoxy)-22-oxodocosanoic acid |
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| Synonym | More Synonyms |
| Description | 22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t |
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| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C26H50O4 |
|---|---|
| Molecular Weight | 426.673 |
| Exact Mass | 426.370911 |
| 22-[(2-Methyl-2-propanyl)oxy]-22-oxodocosanoic acid |
| Docosanedioic acid, mono(1,1-dimethylethyl) ester |