3-Mercaptopropionic acid NHS ester
Modify Date: 2024-02-01 11:46:00
3-Mercaptopropionic acid NHS ester structure
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Common Name | 3-Mercaptopropionic acid NHS ester | ||
|---|---|---|---|---|
| CAS Number | 117235-10-6 | Molecular Weight | 203.21600 | |
| Density | 1.40±0.1 g/cm3 | Boiling Point | 318.4±44.0 °C | |
| Molecular Formula | C7H9NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-Mercaptopropionic acid NHS ester3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | (2,5-dioxopyrrolidin-1-yl) 3-sulfanylpropanoate |
|---|---|
| Synonym | More Synonyms |
| Description | 3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
| References |
| Density | 1.40±0.1 g/cm3 |
|---|---|
| Boiling Point | 318.4±44.0 °C |
| Molecular Formula | C7H9NO4S |
| Molecular Weight | 203.21600 |
| Exact Mass | 203.02500 |
| PSA | 102.48000 |
| Hazard Codes | Xi |
|---|
| 3-Mercapropropanoyl-N-hydroxysuccinimide ester |
| 1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione |